A gift card to their favorite store or favorite restaurant. That way you don’t have to guess what they need/want to buy for their home or themselves.
Put any amount that you can afford.
For example, most people shop at Target, Walmart, Kmart, and people like to eat out at Olive Garden. They all have gift cards to those stores.
You can put the gift card in a little box and gift wrap it with a ribbon on top.
I have given gift cards to different occassions and the recipients often use it. I know cuz I am nosy and I check the balance

If they have a new baby I’m sure they could use a night out, how about a gift card to a restaurant, and offer to babysit.

housecleaning service for one day

Since she’s your friend, you should have an idea of the types of things she likes, but if you’re unsure of what she has for her house already, you could either ask her what she needs, or get something personalized for her.

For example, a picture frame, or a pair of mugs, or something like that.

This probably sounds really dull but a couple of sets of neutral colored towels are always a good gift especially for someone who’s just gotten a new home. A pretty fall wreath would also be a nice gift. A set of nice candle holders is also lovely. Personally, I’d love to get the towels or Christmas ornaments as these are two things that I never seem to have enough of.